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Genetic Testing for Breast and Ovarian Cancer

October 27, 2014whsmdBlog


 

Genetic Testing for Breast and Ovarian Cancer

Having a strong family history of breast or ovarian cancer can increase your risk of developing these cancers.  Genetic testing should be considered for women who have:

1. multiple close family members affected with breast or ovarian cancer particularly if it occurred under age 50.

2. A close family member with more than one type of cancer.

3. Multiple generations of close family members with cancer.  The family history on the father’s side is as important as the mother’s side.

4. Other cancers besides ovarian and breast in families may also be suggestive of hereditary disease, like pancreatic, prostate and colon cancer.

What is genetic testing?

Cancer develops because of mutations/defects in one or more genes.  Cancer can develop by acquired mutations that are not inherited.  About 5-10% of breast cancers are germline mutations that can pass from parent to child.  

BRCA1 and BRCA2 are examples of genes that can be tested for.  This is a simple blood test that can be performed in our office.  Before you have genetic testing you should discuss these issues with your physician.  There are medical, emotional and financial issues that can affect you and your family.  

 

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